| Publications by used technique | Progenetix cases by disease class | List entities for hot spot | ||
|---|---|---|---|---|
|
|
Publications with Comparative Genomic Hybridization (CGH) data |
|
Entities according to ICD-O 3 | |
|
|
Publications with array/matrix CGH data (whole genome BAC, oligonucleotide, cDNA, SNP) |
|
Disease loci (e.g. all gastric tumors) | |
|
|
Tumor-cytogenetic publications, mostly from the Mitelman Database of Chromosome Aberrations in Cancer |
|
Compound groups (e.g. prostate ca. as "adenocarcinoma" of "prostate gland") | |
Example: Regional genomic imbalances in >1800 squamous cell carcinomas
The Progenetix database provides an overview of copy number abnormalities in human cancer from Comparative Genomic Hybridization (CGH) experiments. As a curated database, it collects genomic gain/loss information of individual cancer and leukemia cases, published in peer reviewed journals.
25725 cases from 896 publications: Progenetix is with 19438 CGH and 6246 array CGH experiments the largest public database for interpreted ("called") whole genome CGH profiles. Additionally, the website lists all publications referring to (a)CGH experiments. Progenetix users are encouraged to submit their (a)CGH data. Database & software are developed by the group of Michael Baudis at the University of Zürich.
Related publications
Baudis, M. 2007. Genomic imbalances in 5918 malignant epithelial tumors: An explorative meta-analysis of chromosomal CGH data. BMC Cancer 7:226 [PDF]
Baudis, M. 2006. Online database and bioinformatics toolbox to support data mining in cancer cytogenetics. Biotechniques 40, no. 3: 296-272. [PDF]
Baudis, M, and ML Cleary. 2001. Progenetix.net: an online repository for molecular cytogenetic aberration data. Bioinformatics 12, no. 17: 1228-1229. [PDF]