progenetix - database of cytogenetic abnormalities in cancer
| Selection by article | Selection by disease class | ||
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Publications including chromosomal Comparative Genomic Hybridization (CGH) experiments |
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Specific disease entities according to ICD-O 3 |
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Publications containing array/matrix CGH data (BAC, oligonucleotide, cDNA, SNP) for whole-genome profiling |
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Disease loci (e.g. all gastric tumors, irrespective of histology) |
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Tumor-cytogenetic publications, mostly derived from the "Mitelman Database of Chromosome Aberrations in Cancer" |
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Compound groups, e.g. clinico-pathological entities (prostate ca. as combination of "adenocarcinoma" with locus "prostate gland") |
Baudis, M. 2007. Genomic imbalances in 5918 malignant epithelial tumors: An explorative meta-analysis of chromosomal CGH data. BMC Cancer 7:226 [PDF]
Baudis, M. 2006. Online database and bioinformatics toolbox to support data mining in cancer cytogenetics. Biotechniques 40, no. 3: 296-272. [PDF]
Baudis, M, and ML Cleary. 2001. Progenetix.net: an online repository for molecular cytogenetic aberration data. Bioinformatics 12, no. 17: 1228-1229. [PDF]
License terms for the data base can be found here. For academic users, registration is only necessary for source downloads and online analysis of the database content, but not for the use of the static website. Requests usually will be processed over the next day(s).
Progenetix collects information about changes in the chromosomes (chromosomal rearrangements) and genomic composition of cancer and leukemia cases. It consists of a compilation of published data from Comparative Genomic Hybridization (CGH), array CGH and matrix CGH (aCGH) experiments, as well as from some studies using Metaphase analysis (Giemsa banding, SKY, MFISH). Progenetix is with 17247 CGH and 1930 array CGH experiments by far the largest public CGH database. The software and database content are maintained by Michael Baudis.













